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The Center for Reproductive Medicine and Robotic Surgery is a state of art IVF center providing advanced Assisted Reproductive Treatment services, including intrauterine insemination (IUI), in-vitro fertilization (IVF), Intracytoplasmic Sperm injection (ICSI), Pre-Implantation Genetic Testing – Aneuploidy (PGT-A), embryo biopsy for sex selection, Donor Oocyte program, Surrogacy program, Testicular sperm extraction ( TESA). The Center also evaluate and treat patients with polycystic ovary syndrome (PCOS), endometriosis, premature ovarian failure, congenital anomalies of genital tract, fibroid uterus, ovarian cysts, pelvic pain syndrome, menopausal disorders etc.

Dr. Jacob is a robotic surgeon and a national proctor who trains doctors in Robotic Surgery. The Center offers Robotic surgery for complex infertility conditions like stage IV endometriosis, microsurgical tubal reversal surgery, myomectomy (fibroid removal surgery) etc. He is a Board Certified Obstetrician and Gynecologist and a Reproductive Endocrinology and Infertility Specialist. He is also a Fellow of the American Board of Obstetricians and Gynecologists and Royal College of Obstetricians & Gynecologists (UK). He is a member of the American Society for Reproductive Medicine (ASRM) and European Society for Human Reproduction (ESHRE).

We are located in St. Louis, the heart of the Midwest Рonly 10 minutes from St. Louis Lambert Field Airport, providing services for patients locally and around the world. We are currently accepting new patients and welcome the opportunity to help you fulfill your dreams of having a child.

Success Rates

We are excited to share our success rates; The overall pregnancy rate of 2015 was 76% per embryo transfer. 77% Success Rate for infertility due to Endometriosis. Our overall pregnancy per embryo transfer success rate for 2017 is 81.08%.


< 35 Years


> 35 Years


Egg Donor


Dr. Saji Jacob


Ashley Graham

Office Manager

At The Center for Reproductive Medicine and Robotic Surgery(CRMRS) we provide private, professional and compassionate fertility care. Dr. Jacob and our reproductive team provide a very personalized approach, from diagnostic assessment and early intervention through high-tech procedures like In Vitro Fertilization (IVF), and Intracytoplasmic Sperm Insertion (ICSI), intrauterine insemination (IUI) and Pre-Implantation Genetic Testing – Aneuploidy (PGT-A).

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