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The Center for Reproductive Medicine and Robotic Surgery is a state of art IVF center providing advanced Assisted Reproductive Treatment services, including intrauterine insemination (IUI), in-vitro fertilization (IVF), Intracytoplasmic Sperm injection (ICSI), Pre-Implantation Genetic Testing – Aneuploidy (PGT-A), embryo biopsy for sex selection, Donor Oocyte program, Surrogacy program, Testicular sperm extraction ( TESA). The Center also evaluate and treat patients with polycystic ovary syndrome (PCOS), endometriosis, premature ovarian failure, congenital anomalies of genital tract, fibroid uterus, ovarian cysts, pelvic pain syndrome, menopausal disorders etc.

Dr. Jacob is a robotic surgeon and a national proctor who trains doctors in Robotic Surgery. The Center offers Robotic surgery for complex infertility conditions like stage IV endometriosis, microsurgical tubal reversal surgery, myomectomy (fibroid removal surgery) etc. He is a Board Certified Obstetrician and Gynecologist and a Reproductive Endocrinology and Infertility Specialist. He is also a Fellow of the American Board of Obstetricians and Gynecologists and Royal College of Obstetricians & Gynecologists (UK). He is a member of the American Society for Reproductive Medicine (ASRM) and European Society for Human Reproduction (ESHRE).

We are located in St. Louis, the heart of the Midwest – only 10 minutes from St. Louis Lambert Field Airport, providing services for patients locally and around the world. We are currently accepting new patients and welcome the opportunity to help you fulfill your dreams of having a child.

Success Rates

We are excited to share our success rates; The overall pregnancy rate of 2015 was 76 % per embryo transfer. 77 % Success Rate for infertility due to Endometriosis. Our overall pregnancy per embryo transfer success rate for 2017 is 81.08 % and our current success rate for 2019 is 88 %.




Dr. Saji Jacob


The mission of my dream is simple: Make the dream of having a child affordable to all infertile couples by providing the best care, at an affordable price and in a friendly and compassionate environment. We are proud to offer a comprehensive array of services, in a responsive and efficient manner.  Our single office setting enables us to have complete control over your care which provides you with a convenience that other centers may not be able to offer. We also provide extended office hours to ensure your care fits into your busy schedule. My staff and I are committed to exceeding your expectations  and are confident you will find our office convenient, affordable, and run by a dedicated and caring staff.


Ashley Graham

Office Manager

“I have definitely found myself right at home here at our center. Having been an IVF patient in the past, as well as one of Dr. Jacob’s robotic surgery patients, it really means a lot to me to be able to work with our patients as they go through testing and treatment. I work closely with insurance companies, pharmacies, pharmaceutical companies, and medical providers to help obtain the best possible outcomes for our patients. I remember feeling very overwhelmed by the infertility process and always wished someone would have taken an extra minute or two to help me understand what was happening. I really enjoy taking that extra minute now with our patients and am happy to go that extra mile when necessary”.

At The Center for Reproductive Medicine and Robotic Surgery(CRMRS) we provide private, professional and compassionate fertility care. Dr. Jacob and our reproductive team provide a very personalized approach, from diagnostic assessment and early intervention through high-tech procedures like In Vitro Fertilization (IVF), and Intracytoplasmic Sperm Insertion (ICSI), intrauterine insemination (IUI) and Pre-Implantation Genetic Testing – Aneuploidy (PGT-A).

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