The number of specimens to be cryostored may be different for each patient depending on social and biological factors. Your age, marital status, and number of children that you presently have are some of the social factors to consider. Semen quality, health, and your partner’s fertility status may be among some of the biological factors to keep in mind when deciding the number of semen specimens to have frozen. You should also consider the overall pregnancy rates and cost of the currently available reproductive technologies. Pregnancy rates for intrauterine insemination (IUI) or in-vitro fertilization (IVF) are about 20% and 40-70% respectively. For IUI you may need more than one ejaculate; for IVF a single one may only be necessary. For male factor infertility patients with very low sperm counts there is an additional technology available: Intra-Cytoplasmic Sperm Injection (ICSI). Once you weigh all the factors described above you may have an idea about the number of specimens you want to freeze. Let us suppose that in the best of scenarios you are a healthy male, contemplating a vasectomy, have an average or above sperm quality, have a stable family and children, and you want to have semen frozen just for “peace of mind”, you may want to freeze a single ejaculate. In a different scenario if your sperm quality is below average, you have no children, and have health problems that may impair your ability to produce sperm, you may want to play safe and have more than one specimen frozen.